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 ヒトゲノムネットワークプラットフォーム構築 |
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| 研究課題 | 垂直統合型細胞内分子相互作用ネットワーク分析情報基盤の開発 |
| 研究期間 | 平成16年度〜20年度 |
| 研究課題代表者 | 北野 宏明 |
| 所属機関 | 特定非営利活動法人 システム・バイオロジー研究機構 |
| 公開システム | CellDesigner |
| 研究目的 | 本研究では、ゲノムネットワークを記述し、それを通じて情報へとアクセスができるソフトウエアプラットフォームの開発を行う。 |
| 研究概要 | 研究課題代表者が開発しているシステムバイオロジーマークアップ言語（SBML:http://sbml.org/）、分子間相互作用記述言語(SBGN:http://sbgn.org/)、CellDesigner分子相互作用エディター（http://celldesigner.org/）などを拡張・強化し、これらの多様な情報の記述と解析に対応させる。 |
| 研究成果 | SBMLは、SBML Level-2 Version 4の最終仕様の決定、SBGNは、SBGN Level-1の仕様のうち Process Diagram の仕様をリリース、残りのActivity Flow, Entity Relationshipの2記法の仕様の決定に近づきつつある。特に、SBGNは、新たな標準化作業であるにも関わらず、大きな関心と多くの参加を得て進められている。これらの標準仕様案を実際に実装したソフトウエア、CellDesignerは、ゲノムネットワークプロジェクトで同定される遺伝子間の制御関係の記述の強化を行うと共に、Plug-Inなどを可能とする機能強化を行った第4版を、20年度にリリースした。 |
| データ種別 | - |
| 対象生物 | - |
| 組織・細胞株 | - |
| 対象遺伝子 | - |
| 実験情報 | - |
| 産出データ （ダウンロード） |
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| XMLデータ | - |
| 研究論文・特許出願・ 学術発表など |
------------------------------ PUBLICATION ------------------------------
PUBLICATION ID:213 PUBLICATION TYPE: journal PUBLICATION NAME: nature biotechnology August 2005, Volume 23 No 8 ARTICLE TITLE: Using process diagrams for the graphical representation of biological networks SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2005-08-04 TITLE: Using process diagrams for the graphical representation of biological networks STATUS: Published AUTHOR NAME: Hiroaki Kitano1, 2, 3, 4, Akira Funahashi1, 3, 4, Yukiko Matsuoka1, 3 & Kanae Oda1, 4 AUTHOR AFFILIATION: 1 The Systems Biology Institute, Suite 6A, M31 6-31-15 Jingumae, Shibuya, Tokyo, 150-0001 Japan. 2 Sony Computer Science Laboratories, Inc., 3-14-13 Higashi-gotanda, Shinagwa, Tokyo, 141-0022 Japan. 3 ERATO-SORST Kitano Symbiotic Systems Project, Japan Science and Technology Agency, Suite 6A, M31 6-31-15 Jingumae, Shibuya, Tokyo, 150-0001 Japan. 4 Department of Fundamental Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku, Yokohama 223-8522 Japan. ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:811 PUBLICATION TYPE: journal PUBLICATION NAME: Molecular Systems Biology ARTICLE TITLE: A comprehensive map of the toll-like receptor signaling network. Molecular Systems Biology SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2006-04-20 TITLE: A comprehensive map of the toll-like receptor signaling network. Molecular Systems Biology STATUS: Published AUTHOR NAME: Oda, K.1, 2; Kitano, H.1,2,3 AUTHOR AFFILIATION: 1. The Systems Biology Institute; 2. Department of Fundamental Science and Technology, Keio University; 3. Sony Computer Science Laboratories, Inc. ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:815 PUBLICATION TYPE: Book PUBLICATION NAME: System Modeling in Cellular Biology ARTICLE TITLE: Software Infrastructure for Effective Communication and Reuse of Computational Models SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2006-04-01 TITLE: Software Infrastructure for Effective Communication and Reuse of Computational Models STATUS: Published AUTHOR NAME: Andrew Finney, Michael Hucka, Benjamin J. Bornstein, Sarah M. Keating, Bruce E. Shapiro, Joanne Matthews, Ben L. Kovitz, Maria J. Schilstra, Akira Funahashi, Hiroaki Kitano AUTHOR AFFILIATION: The Systems Biology Institute, etc. ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:819 PUBLICATION TYPE: Conference PUBLICATION NAME: ESF-JSPS Follow-up Workshop on Functional Genomics From the Bench to Bioinformatics ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2006-03-07 TITLE: The theory of biological robustness and its applications to medicine STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:820 PUBLICATION TYPE: journal PUBLICATION NAME: 医学のあゆみ ARTICLE TITLE: 生物学的ロバストネスとゲノムワイド・ネットワーク SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2006-12-02 TITLE: 生物学的ロバストネスとゲノムワイド・ネットワーク STATUS: Published AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: 株式会社ソニーコンピュータサイエンス研究所; 特定非営利活動法人システム・バイオロジー研究機構; 癌研究会癌研究所システムバイオロジー部 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:824 PUBLICATION TYPE: journal PUBLICATION NAME: Nature Reviews Drug Discovery ARTICLE TITLE: A robustness-based approach to systems-oriented drug design SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2007-02-23 TITLE: A robustness-based approach to systems-oriented drug design STATUS: Published AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: Sony Computer Science Laboratories, Inc.; The Systems Biology Institute; Department of Cancer Systems Biology, The Cancer Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:829 PUBLICATION TYPE: journal PUBLICATION NAME: In Silico Biology ARTICLE TITLE: Integration of CellDesigner and SABIO-RK SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2007-03-26 TITLE: Integration of CellDesigner and SABIO-RK STATUS: Published AUTHOR NAME: Funahashi, A.1,2,3,4; Jouraku, A.1,5; Matsuoka, Y.1,4; Kitano, H.1,3,4,6 AUTHOR AFFILIATION: 1 JST/ERATO-SORST Kitano Symbiotic Systems Project, Japan 2 School of Medicine, Keio University, Japan 3 School of Fundamental Science and Technology, Keio University, Japan 4 The Systems Biology Institute, Japan 5 School of Science for Open and Environmental Systems, Keio University, Japan 6 Sony Computer Science Laboratories, Inc., Japan ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:832 PUBLICATION TYPE: Conference PUBLICATION NAME: International Specialised Symposium on Yeasts. ISSY25. Systems Biology of Yeasts – From Models to Applications. ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2006-06-21 TITLE: Biological Robustness STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:834 PUBLICATION TYPE: Conference PUBLICATION NAME: 花王株式会社 生物科学研究所 講演会 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2006-07-05 TITLE: The theory of biological robustness and its applications to medicine STATUS: Presented AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: 特定非営利活動法人システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:837 PUBLICATION TYPE: Conference PUBLICATION NAME: 17th International Symposium on Mathematical Theory of Networks and Systems ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2006-07-25 TITLE: The theory of biological robustness and its applications to medicine STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:839 PUBLICATION TYPE: Conference PUBLICATION NAME: ＳＩＣＥ制御部門生物制御調査研究会第５回会合 Frontier Research System 20th Anniversary: International Workshop on Recent Advances in Biological Control ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2006-07-29 TITLE: The theory of biological robustness and its applications to medicine STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:841 PUBLICATION TYPE: Conference PUBLICATION NAME: Towards 2020 Science Forum ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2006-09-04 TITLE: Towards the Fundamental System Theory in Biology: The Theory of Biological Robustness STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Insitute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:843 PUBLICATION TYPE: Conference PUBLICATION NAME: 日本学術振興会ゲノムテクノロジー第164委員会 第3期キックオフシンポジウム 「環境から医学まで：ゲノムテクノロジーが変えるバイオ戦略」 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2006-09-26 TITLE: 生物学的ロバストネス理論と医療への応用 STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:845 PUBLICATION TYPE: Conference PUBLICATION NAME: 第65回 日本癌学会学術総会 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2006-09-29 TITLE: 癌のロバストネス STATUS: Presented AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: 特定非営利活動法人システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:848 PUBLICATION TYPE: Conference PUBLICATION NAME: ICSB 2006 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2006-10-09 TITLE: Issues in Systems Biology STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:850 PUBLICATION TYPE: Conference PUBLICATION NAME: ICSB 2006 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2006-10-09 TITLE: CellDesigner3.1: a process diagram editor for gene-regulatory and biochemical networks STATUS: Presented AUTHOR NAME: Funahashi, A.; Jouraku, A.; Matsuoka, Y.; Kikuchi, N.; Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute, etc. ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:853 PUBLICATION TYPE: Conference PUBLICATION NAME: ICSB 2006 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2006-10-09 TITLE: Sysetms biology graphical notation (SBGN) project STATUS: Presented AUTHOR NAME: Kitano, H.; Hucka, M.; Novere, Le N.; Funahashi, A. AUTHOR AFFILIATION: The Systems Biology Institute, etc. ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:856 PUBLICATION TYPE: Conference PUBLICATION NAME: GeneSpring「アレイデータ解析セミナー」 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2006-10-31 TITLE: Foundations of Sysytems Biology STATUS: Presented AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: 特定非営利活動法人システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:858 PUBLICATION TYPE: Conference PUBLICATION NAME: The 3rd International E. Coli Alliance Conference on Systems Biology 2006 (IECA 2006) ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2006-11-02 TITLE: Biological Robustness STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:860 PUBLICATION TYPE: Conference PUBLICATION NAME: Winter Simulation Conference (WSC) 2006 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2006-12-06 TITLE: CellDesigner: A Modeling Tool for Biochemical Networks STATUS: Presented AUTHOR NAME: Funahashi, A.; Matsuoka, Y.; Jouraku, A.; Kikuchi, N.; Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute, etc. ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:863 PUBLICATION TYPE: Conference PUBLICATION NAME: 第2回「四国工業研究会 次世代バイオナノ研究会」 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2006-12-08 TITLE: 癌のロバストネス STATUS: Presented AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: 特定非営利活動法人システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:865 PUBLICATION TYPE: Conference PUBLICATION NAME: Evolving Life Life Evolving: ELLE ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2006-12-20 TITLE: The theory of biological robustness and its applications to medicine STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:879 PUBLICATION TYPE: Conference PUBLICATION NAME: Computational Cell Biology ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2007-03-06 TITLE: CELLDESIGNER3.5: A PROCESS DIAGRAM EDITOR FOR GENE-REGULATORY AND BIOCHEMICAL NETWORKS STATUS: Presented AUTHOR NAME: Funahashi, A.; Jouraku, A.; Matsuoka, Y.; Kikuchi, N.; Ki AUTHOR AFFILIATION: The Systems Biology Institute, etc. ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:880 PUBLICATION TYPE: Conference PUBLICATION NAME: 情報処理学会 第69回全国大会 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2007-03-07 TITLE: システムバイオロジー研究の最前線 STATUS: Presented AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: 特定非営利活動法人システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:881 PUBLICATION TYPE: Conference PUBLICATION NAME: 慶應義塾大学COEグローバルシンポジウム： ケミカルバイオロジーとシステムバイオロジーの融合 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2007-03-10 TITLE: 生物学的ロバストネスの理論とその応用 STATUS: Presented AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: 特定非営利活動法人システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:882 PUBLICATION TYPE: Conference PUBLICATION NAME: Leica Scientific Forum Heidelberg ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2007-03-12 TITLE: The theory of biological robustness and its applications to medicine STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:883 PUBLICATION TYPE: Conference PUBLICATION NAME: USGEB 2007 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2007-03-13 TITLE: Network, Robustness and Drug Design STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:884 PUBLICATION TYPE: Conference PUBLICATION NAME: MCISB Systems Biology Minisymposium ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2007-04-24 TITLE: Robustness STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:885 PUBLICATION TYPE: Conference PUBLICATION NAME: Pharmaceutical Sciences World Congress 2007 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2007-04-25 TITLE: The theory of biological robustness and its applications to medicine STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:886 PUBLICATION TYPE: Conference PUBLICATION NAME: Days of Molecular Medicine 2007: Emerging Technologies and Cancer Biology ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2007-05-24 TITLE: Robustness-based approach for systems-oriented drug design: Toward "long-tail drugs" STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:887 PUBLICATION TYPE: Book PUBLICATION NAME: Introduction to Systems Biology ARTICLE TITLE: CellDesigner: A Graphical Biological Network Editor and Workbench Interfacing Simulator. SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2007-07-01 TITLE: CellDesigner: A Graphical Biological Network Editor and Workbench Interfacing Simulator. STATUS: Published AUTHOR NAME: Funahashi, A.; Morohashi, M.; Matsuoka, Y.; Jouraku, A.; Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute, etc. ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:888 PUBLICATION TYPE: Book PUBLICATION NAME: Introduction to Systems Biology ARTICLE TITLE: Scientific Challenges in Systems Biology SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2007-07-01 TITLE: Scientific Challenges in Systems Biology STATUS: Published AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:890 PUBLICATION TYPE: Conference PUBLICATION NAME: Systems Biology Workshop ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2007-07-11 TITLE: Biological Robustness and Drug Design STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:891 PUBLICATION TYPE: Conference PUBLICATION NAME: ゲノムネットワークプロジェクト 第２回発現クラスターワクショップ（Expression Cluster Workshop）メインミーティング ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2007-07-18 TITLE: Representing Genome Network in SBGN and SBML using CellDesigner STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:892 PUBLICATION TYPE: Conference PUBLICATION NAME: XXX Congress of The Spanish Biochemical Society ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2007-09-12 TITLE: A robustness-based approach to systems-oriented drug design STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:893 PUBLICATION TYPE: journal PUBLICATION NAME: Biological Theory ARTICLE TITLE: Self-Extending Symbiosis: A Mechanism for Increasing Robustness Through Evolution SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2006-05-22 TITLE: Self-Extending Symbiosis: A Mechanism for Increasing Robustness Through Evolution STATUS: Published AUTHOR NAME: Kitano, H.; Oda, K. AUTHOR AFFILIATION: The Systems Biology Institue, etc. ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:894 PUBLICATION TYPE: journal PUBLICATION NAME: Nature Reviews Molecular Cell Biology ARTICLE TITLE: Computational cellular dynamics: a network-physics integral SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2006-03-01 TITLE: Computational cellular dynamics: a network-physics integral STATUS: Published AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:895 PUBLICATION TYPE: journal PUBLICATION NAME: Molecular Systems Biology ARTICLE TITLE: Robustness trade-offs and host-microbial symbiosis in immune system SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2006-01-01 TITLE: Robustness trade-offs and host-microbial symbiosis in immune system STATUS: Published AUTHOR NAME: Kitano, H.; Oda, K. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:896 PUBLICATION TYPE: journal PUBLICATION NAME: Molecular Systems Biology ARTICLE TITLE: A comprehensive pathway map of epidermal growth factor receptor signaling SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2005-05-25 TITLE: A comprehensive pathway map of epidermal growth factor receptor signaling STATUS: Published AUTHOR NAME: Oda, K.; Matsuoka, Y.; Funahashi, A.; Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:897 PUBLICATION TYPE: journal PUBLICATION NAME: Nature Biotechnology ARTICLE TITLE: Using process diagrams for the graphical representation of biological networks SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2005-08-04 TITLE: Using process diagrams for the graphical representation of biological networks STATUS: Published AUTHOR NAME: Kitano, H.; Funahashi, A.; Matsuoka, Y.; Oda, K. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:898 PUBLICATION TYPE: journal PUBLICATION NAME: Nature Reviews Genetics ARTICLE TITLE: Biological Robustness SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2004-11-01 TITLE: Biological Robustness STATUS: Published AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:899 PUBLICATION TYPE: journal PUBLICATION NAME: Topics in Current Genetics ARTICLE TITLE: Scientific and Technical Challenges for Systems Biology SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2005-11-01 TITLE: Scientific and Technical Challenges for Systems Biology STATUS: Published AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:900 PUBLICATION TYPE: journal PUBLICATION NAME: バイオテクノロジージャーナル ARTICLE TITLE: <序文>システムバイオロジーにおける基本概念としてのロバストネス SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2004-12-20 TITLE: <序文>システムバイオロジーにおける基本概念としてのロバストネス STATUS: Published AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: 特定非営利活動法人システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:901 PUBLICATION TYPE: journal PUBLICATION NAME: バイオテクノロジージャーナル ARTICLE TITLE: システムバイオロジー産業の動向 ～シミュレーションを用いたバイオビジネス SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2004-12-20 TITLE: システムバイオロジー産業の動向 ～シミュレーションを用いたバイオビジネス STATUS: Published AUTHOR NAME: 諸橋峰雄; 北野宏明 AUTHOR AFFILIATION: 特定非営利活動法人システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:902 PUBLICATION TYPE: journal PUBLICATION NAME: 蛋白質 核酸 酵素 2004年12月号増刊 ゲノムネットワーク ARTICLE TITLE: ゲノムワイドなネットワーク・アーキテクチュアの理論 SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2004-12-15 TITLE: ゲノムワイドなネットワーク・アーキテクチュアの理論 STATUS: Published AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: 特定非営利活動法人システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:903 PUBLICATION TYPE: journal PUBLICATION NAME: 月刊「BIO INDUSTRY」 ARTICLE TITLE: 癌のシステムバイオロジー -腫瘍頑健性理論とは？- SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2004-08-12 TITLE: 癌のシステムバイオロジー -腫瘍頑健性理論とは？- STATUS: Published AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: 特定非営利活動法人システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:904 PUBLICATION TYPE: Conference PUBLICATION NAME: 3rd International Conference on Functional Genomics of Aging ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2006-03-31 TITLE: The theory of biological robustness and its applications to medicine STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:905 PUBLICATION TYPE: Conference PUBLICATION NAME: BBSRC/EPSRC National Workshop Systems Biology ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2006-03-16 TITLE: The Scope of Systems Biology STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:906 PUBLICATION TYPE: Conference PUBLICATION NAME: ESF-JSPS Follow-up Workshop on Functional Genomics From the Bench to Bioinformatics ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2006-03-07 TITLE: The theory of biological robustness and its applications to medicine STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:907 PUBLICATION TYPE: Conference PUBLICATION NAME: 第28会日本分子生物学会年会 ワークショップ：W3O「システムバイオロジーとはなにか」 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2005-12-09 TITLE: システムバイオロジーとはなにか？雲のつかみかたに関する一考察 STATUS: Presented AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: 特テ非営利活動法人システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:908 PUBLICATION TYPE: Conference PUBLICATION NAME: 第８回ヒューマンサイエンス総合研究ワークショップ「システムバイオロジーが拓く未来創薬／医療」 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2005-11-25 TITLE: 生物学的ロバストネス理論とがんへのアプローチ STATUS: Presented AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: 特定非営利活動法人システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:909 PUBLICATION TYPE: Conference PUBLICATION NAME: ゲノム・遺伝子発現研究戦略作業部会：ゲノムネットワーク研究の戦略的展開に関する打合せ ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2005-11-17 TITLE: システムバイオロジーの展開 STATUS: Presented AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: 特定非営利活動法人システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:910 PUBLICATION TYPE: Conference PUBLICATION NAME: BioPAX Japan F2F meeting techcical workshop ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2005-11-17 TITLE: CellDesigner STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:911 PUBLICATION TYPE: Conference PUBLICATION NAME: 神奈川科学技術アカデミー教育講座バイオインフォマティクスコース ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2005-11-15 TITLE: システムバイオロジー概論 STATUS: Presented AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: 特定非営利活動法人システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:912 PUBLICATION TYPE: Conference PUBLICATION NAME: Ernst Schering Research Foundation Workshop "Systems Biology - Applications and Perspectives" ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2005-11-11 TITLE: Cancer as a robust system: implications for anticancer therapy STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:913 PUBLICATION TYPE: Conference PUBLICATION NAME: Agilent Laboratories ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2005-11-09 TITLE: Biological Robustness STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:914 PUBLICATION TYPE: Conference PUBLICATION NAME: 文部科学省職員有志勉強会 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2005-10-31 TITLE: システムバイオロジーの現状と展開 STATUS: Presented AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: 特定非営利活動法人システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:915 PUBLICATION TYPE: Conference PUBLICATION NAME: Center for Cancer Systems Biology Seminar ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2005-10-21 TITLE: Theory of cancer robustness and its medical implications STATUS: Presented AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: 特定非営利活動法人システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:916 PUBLICATION TYPE: Conference PUBLICATION NAME: ICSB2005 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2005-10-19 TITLE: A comprehensive map of Toll-like receptor signaling network STATUS: Presented AUTHOR NAME: Kitano, H.; Oda, K. AUTHOR AFFILIATION: The Systems Biology Institute, etc. ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:917 PUBLICATION TYPE: Conference PUBLICATION NAME: Life Science Conference 2005 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2005-10-11 TITLE: The theory of biological robustness and its applications to medicine STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:918 PUBLICATION TYPE: Conference PUBLICATION NAME: 第10回分子細胞生物学研究所シンポジウム「情報生物学」 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2005-09-22 TITLE: Biological robustness and its implications on medicine STATUS: Presented AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: 特定非営利活動法人システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:919 PUBLICATION TYPE: Conference PUBLICATION NAME: ゲノムフォーラム「わが国におけるゲノム研究の現状と今後の課題」 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2005-09-18 TITLE: システムバイオロジーの現状と展望 STATUS: Presented AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: 特定非営利活動法人システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:920 PUBLICATION TYPE: Conference PUBLICATION NAME: 第38回酵母遺伝学フォーラム ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2005-09-05 TITLE: CellDesigner 2.2 を用いた、出芽酵母の細胞周 STATUS: Presented AUTHOR NAME: 小田夏奈江、守屋央朗、松岡由希子、舟橋啓、北野宏明 AUTHOR AFFILIATION: 特定非営利活動法人システム・バイオロジー研究機構、他 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:921 PUBLICATION TYPE: Conference PUBLICATION NAME: Functional Genomics conference ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2005-08-29 TITLE: Biological robustness and its implication to medical practice STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:922 PUBLICATION TYPE: Conference PUBLICATION NAME: Seminar@Karolinska Intitutet ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2005-08-26 TITLE: Biological robustness and its implication to medical practice STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:923 PUBLICATION TYPE: Conference PUBLICATION NAME: 12th European Congress on Biotechnology (ECB12) ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2005-08-22 TITLE: Biological robustness and its implication to medical practice STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:924 PUBLICATION TYPE: Conference PUBLICATION NAME: 癌研セミナー ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2005-07-29 TITLE: Biological robustness and its implications on medicine STATUS: Presented AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: 特定非営利活動法人システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:925 PUBLICATION TYPE: Conference PUBLICATION NAME: International Symposium on Leading Project for Biosimulation Program ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2005-07-07 TITLE: Biolobical robustness STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:926 PUBLICATION TYPE: Conference PUBLICATION NAME: 21世紀COEプログラム「言語から読み解くゲノムと生命システム」特別講義 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2005-06-23 TITLE: Biological Robustness STATUS: Presented AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: 特定非営利活動法人システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:927 PUBLICATION TYPE: Conference PUBLICATION NAME: International Workshop on Systems Biology 2005 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2005-05-12 TITLE: Biological Robustness STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:928 PUBLICATION TYPE: Conference PUBLICATION NAME: JST異分野研究者交流領域探索プログラム「制御生物学の可能性を探る」第五回研究会 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2005-01-25 TITLE: Biological Robustness STATUS: Presented AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: 特定非営利活動法人システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:930 PUBLICATION TYPE: Conference PUBLICATION NAME: First FEBS Advanced Course on Systems Biology: From Molecules & Modeling To Cells ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2005-03-16 TITLE: CellDesigner2.0: A process diagram editor for gene-regulatory and biochemical networks STATUS: Presented AUTHOR NAME: Funahashi, A.; Tanimura, N.; Matsuoka, Y.; Yoshinaga, N.; Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:931 PUBLICATION TYPE: Conference PUBLICATION NAME: Seminar@IMB, The Univ of Queensland ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2005-03-03 TITLE: Biological Robustness STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:932 PUBLICATION TYPE: Conference PUBLICATION NAME: RTK Consortium Meeting ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2005-01-19 TITLE: Biological Robustness STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:934 PUBLICATION TYPE: Conference PUBLICATION NAME: Talk @ University of Hawaii ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2005-01-07 TITLE: Biological Robustness and life in deep sea, space, and other extreme environment STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:936 PUBLICATION TYPE: Conference PUBLICATION NAME: GIW2004 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2004-12-13 TITLE: CellDesigner2.0: A Process Diagram Editor for Gene-regulatory and Biochemical Networks STATUS: Presented AUTHOR NAME: Funahashi, A.; Tanimura, N.; Matsuoka, Y.; Yoshinaga, N.*; Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:937 PUBLICATION TYPE: Conference PUBLICATION NAME: 神奈川科学技術アカデミー教育講座バイオインフォマティクスコース ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2004-11-29 TITLE: システムバイオロジー概論 STATUS: Presented AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: 特定非営利活動法人システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:938 PUBLICATION TYPE: Conference PUBLICATION NAME: 5th International Conference on Systems Biology (ICSB2004) ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2004-10-09 TITLE: Converting the KEGG Pathway Database to SBML STATUS: Presented AUTHOR NAME: Funahashi, A..; Jyoraku, A.; Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:939 PUBLICATION TYPE: Conference PUBLICATION NAME: The Abdus Salam International Centre for Theoretical Physics 40th Anniversary Conference ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2004-10-04 TITLE: Robustness as the fundamental organizational principle of biological systems STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:940 PUBLICATION TYPE: Conference PUBLICATION NAME: 招待講演＠武田薬品工業 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2004-08-05 TITLE: Cancer as a robust system STATUS: Presented AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: 特定非営利活動法人システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:941 PUBLICATION TYPE: Conference PUBLICATION NAME: 癌研セミナー ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2004-04-21 TITLE: Cancer as a Robust System STATUS: Presented AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: 特定非営利活動法人システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:942 PUBLICATION TYPE: Conference PUBLICATION NAME: ICSB 2005 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2005-10-23 TITLE: CellDesigner3.0: A Process Diagram Editor for Gene-regulatory and Biochemical Networks. STATUS: Presented AUTHOR NAME: Akira Funahashi AUTHOR AFFILIATION: ERATO-SORST Kitano Symbiotic Systems Project, JST ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:944 PUBLICATION TYPE: journal PUBLICATION NAME: バイオテクノロジージャーナル ARTICLE TITLE: システムバイオロジー研究のためのソフトウェア標準化. SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2004-01-01 TITLE: システムバイオロジー研究のためのソフトウェア標準化. STATUS: Published AUTHOR NAME: 舟橋 啓 AUTHOR AFFILIATION: 科学技術振興機構ERATO北野共生システムプロジェクト ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:946 PUBLICATION TYPE: Conference PUBLICATION NAME: 9th Workshop on Software Platforms for Systems Biology ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2004-10-14 TITLE: CellDesigner and Hardware Accelerated Simulator STATUS: Presented AUTHOR NAME: Akira Funahashi AUTHOR AFFILIATION: ERATO-SORST Kitano Symbiotic Systems Project, JST ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:948 PUBLICATION TYPE: Conference PUBLICATION NAME: Second BioModels.net training camp ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2007-01-13 TITLE: CellDesigner 4, towards CellDesigner 5. STATUS: Presented AUTHOR NAME: Akira Funahashi AUTHOR AFFILIATION: ERATO-SORST Kitano Symbiotic Systems Project, JST ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:1357 PUBLICATION TYPE: journal PUBLICATION NAME: Molecular Systems Biology ARTICLE TITLE: Towards a theory of biological robustness SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2007-09-18 TITLE: Towards a theory of biological robustness STATUS: Published AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:1358 PUBLICATION TYPE: journal PUBLICATION NAME: 最新医学 9月増刊号 「臨床遺伝子学'07」 ARTICLE TITLE: がんのシステムバイオロジー：腫瘍頑健性理論の視点から SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2007-09-25 TITLE: がんのシステムバイオロジー：腫瘍頑健性理論の視点から STATUS: Published AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: 特定非営利活動法人システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:1359 PUBLICATION TYPE: Book PUBLICATION NAME: したたかな生命 ARTICLE TITLE: したたかな生命 SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2007-11-15 TITLE: したたかな生命 STATUS: Published AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: 特定非営利活動法人システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:1360 PUBLICATION TYPE: Conference PUBLICATION NAME: International Conference on Complexity in Acute Illness ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2007-10-05 TITLE: Systems Biomedicine: A Legitimate Science? STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:1362 PUBLICATION TYPE: Conference PUBLICATION NAME: 21st International Mammalian Genome Conference (IMGC 2007) ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2007-10-28 TITLE: Biological Robustness STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:1364 PUBLICATION TYPE: Conference PUBLICATION NAME: Genomes to Systems Conference 2008 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2008-03-18 TITLE: SBGN: the systems biology graphical notation STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biolgy Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:1372 PUBLICATION TYPE: Conference PUBLICATION NAME: ICSB-2007 (The 8th International conference on Systems Biology) ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2007-10-02 TITLE: CellDesigner 4.0beta: A Modeling Tool for Biochemical Networks STATUS: Presented AUTHOR NAME: Funahashi, A.1,2,*; Yukiko Matsuoka2,3; Akiya Jouraku1,2; Haruka Sugimura2; Yuichi Oikawa2; Norihiro Kikuchi4; Hiroaki Kitano2,3 AUTHOR AFFILIATION: 1. Dept. of Biosciences and Informatics, Keio University, Yokohama, Japan.; 2. The Systems Biology Institute, Tokyo, Japan; 3. JST ERATO-SORST Kitano Symbiotic Systems Project, Tokyo, Japan; 4. Mitsui Knowledge Industry Co., Ltd., Tokyo, Japan ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:1373 PUBLICATION TYPE: journal PUBLICATION NAME: Proceedings of the IEEE (Special Issue Paper) ARTICLE TITLE: CellDesigner 3.5: A Modeling Tool for Biochemical Networks SUBMIT DATE: 2007-11-29 ACCEPT DATE: 2008-08-07 PUBLICATION DATE: 2008-08-07 TITLE: CellDesigner 3.5: A Versatile Modeling Tool for Biochemical Networks STATUS: Published AUTHOR NAME: Funahashi, A.; Yukiko Matsuoka, Akiya Jouraku, Mineo Morohashi, Norihiro Kikuchi, and Hiroaki Kitano AUTHOR AFFILIATION: (A. Funahashi is with the Department of Biosciences and Informatics, Keio University, Yokohama, 223-8522 JAPAN (corresponding author to provide phone: +81-45-566-1797; fax: +81-45-566-1485; e-mail: funa@bio.keio.ac.jp). Y. Matsuoka is with The Systems Biology Institute, Shibuya, Tokyo, 150-0001 JAPAN (e-mail: myukiko@symbio.jst.go.jp). A. Jouraku is with the Department of Biosciences and Informatics, Keio University, Yokohama, 223-8522 JAPAN (e-mail: jouraku@symbio.jst.go.jp). M. Morohashi is with PRTM, Tokyo 163-0430 JAPAN (e-mail: moro@mineo.com). N. Kikuchi is with the Mitsui Knowledge Industry Co., Ltd., Tokyo, 164-8555 JAPAN (e-mail: kikuchi-norihiro@mki.co.jp). H. Kitano is with The Systems Biology Institute, Shibuya, Tokyo, 150-0001 JAPAN (e-mail: kitano@sbi.jp).) ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:1408 PUBLICATION TYPE: Book PUBLICATION NAME: Introduction to Systems Biology (ed. Choi, S., Human Press) ARTICLE TITLE: SBML Models and MathSBML. SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2007-07-01 TITLE: SBML Models and MathSBML. STATUS: Published AUTHOR NAME: Bruce E. Shapiro 1, Andrew Finney 2, Michael Hucka 1, Benjamin Bornstein 1, Akira Funahashi 3, Akiya Jouraku 3, Sarah M. Keating 4, Nicolas Le Novère 5, Joanne Matthews 4, and Maria J. Schilstra 4 AUTHOR AFFILIATION: 1. California Institute of Technology, USA; 2. Physiomics, UK; 3. ERATO-SORST Kitano Symbiotic Systems Project, Japan; 4. University of Hertfordshire, UK; 5. EMBL-EBI, UK; ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:1713 PUBLICATION TYPE: Conference PUBLICATION NAME: The fourth SBGN Workshop: SBGN-4 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2007-10-17 TITLE: CellDesigner 4.1 & Payao plans STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:1714 PUBLICATION TYPE: Conference PUBLICATION NAME: Genomes to Systems 2008 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2008-03-17 TITLE: PathText: Text Mining Integrated with Biological Pathway STATUS: Presented AUTHOR NAME: R. Satre a, B. Kemper a; K. Oda a; N. Okazaki a; Y. Matsuoka b; N. Kikuchi c; H. Kitano b,d; Y. Tsuruoka e; S. Ananiadou f; and J. Tsujii a,f AUTHOR AFFILIATION: a Department of Computer Science, University of Tokyo b The Systems Biology Institute c Mitsui Knowledge Industry Co., Ltd. d Okinawa Institute of Science and Technology e School of Computer Science, University of Manchester f National Centre for Text Mining (NaCTeM) ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:1823 PUBLICATION TYPE: Book PUBLICATION NAME: Systems Biology Graphical Notation: Process Diagram Level 1 Release 1.0 ARTICLE TITLE: Systems Biology Graphical Notation: Process Diagram Level 1 Release 1.0 SUBMIT DATE: 2008-08-15 ACCEPT DATE: 2008-08-15 PUBLICATION DATE: 2008-08-15 TITLE: Systems Biology Graphical Notation: Process Diagram Level 1 Release 1.0 STATUS: Published AUTHOR NAME: Le Novere, N., Moodie, S., Sorokin, A., Hucka, M, Schreiber, F., Demir, E., Mi, H., Matsuoka, Y., Wegner, K., Kitano, H. AUTHOR AFFILIATION: Nicolas Le Novere: EMBL European Bioinformatics Institute, UK; Stuart Moodie: CSBE, University of Edinburgh, UK; Anatoly Sorokin: University of Edinburgh, UK; Michael Hucka: California Institute of Technology, USA; Falk Schreiber: IPK Gatersleben & MLU Halle, Germany; Emek Demir: MSKCC Computational Biology Center, USA; Huaiyu Mi: SRI International, USA; Yukiko Matsuoka: The Systems Biology Institute, Japan; Katja Wegner: University of Hertfordshire, UK; and Hiroaki Kitano: The Systems Biology Institute, Japan ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:1861 PUBLICATION TYPE: Conference PUBLICATION NAME: 理研理事長ファンドワークショップ 理研ライフサイエンス系統合データベースの整備と戦略的研究の推進 －チャンス発見の情報テクノロジー、大規模情報とその活用－ ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2008-10-04 TITLE: システムバイオロジー情報基盤の構想： 次世代パスウェー・データベースの戦略と国際標準化 STATUS: Presented AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:2015 PUBLICATION TYPE: Conference PUBLICATION NAME: 第4回ゲノムネットワークプロジェクト公開シンポジウム ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2008-02-19 TITLE: 生物学的ロバストネスとゲノムネットワーク解析 STATUS: Presented AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: 特定非営利活動法人システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:2016 PUBLICATION TYPE: Book PUBLICATION NAME: オープンシステムサイエンス 原理解明の科学から問題解決の科学へ ARTICLE TITLE: 生物学的ロバストネス －システムバイオロジーからのアプローチ SUBMIT DATE: ACCEPT DATE: 2009-01-22 PUBLICATION DATE: 2009-01-22 TITLE: 生物学的ロバストネス －システムバイオロジーからのアプローチ STATUS: Published AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: ソニーコンピュータサイエンス研究所; システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:2017 PUBLICATION TYPE: Conference PUBLICATION NAME: ESF-UB Conference in Biomedicine: Systems Biology ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2008-04-14 TITLE: Robustness-based approach to systems drug design: toward long-tail drugs STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:2018 PUBLICATION TYPE: Conference PUBLICATION NAME: Microsoft Research Cambridge Seminar ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2008-04-24 TITLE: A robustness-based approach to systems-oriented drug design STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:2019 PUBLICATION TYPE: Conference PUBLICATION NAME: 日本ケミカルバイオロジー研究会 第３回年会 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2008-05-20 TITLE: A robustness-based approach to systems-oriented drug design STATUS: Presented AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:2020 PUBLICATION TYPE: Conference PUBLICATION NAME: 大阪大学臨床医工学融合研究教育センター グローバルCOE in silico medicine 第5回定例シンポジウムフィジオーム・システムバイオロジーの基盤構築と展開 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2008-05-26 TITLE: A robustness-based approach to systems-oriented drug design STATUS: Presented AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:2021 PUBLICATION TYPE: Conference PUBLICATION NAME: 第35回日本トキシコロジー学会学術年会シンポジウム ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2008-06-26 TITLE: システムバイオロジーによる毒性オミクスへのアプローチ "Systems Biology Approach to Toxicomics" STATUS: Presented AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:2022 PUBLICATION TYPE: Conference PUBLICATION NAME: アカデミーヒルズセミナー スクール（RoppongiBIZ）講座 BIZセミナー ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2008-07-03 TITLE: したたかな生命： 進化・生存のカギを握るロバストネスとは何か STATUS: Presented AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:2023 PUBLICATION TYPE: Conference PUBLICATION NAME: 日本人類遺伝学会 第53回大会 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2008-09-28 TITLE: 生物学的ロバストネスとシステム創薬へのアプローチ STATUS: Presented AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:2024 PUBLICATION TYPE: Conference PUBLICATION NAME: KAST教育講座 「システムバイオロジーの新展開」 ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2008-10-02 TITLE: システムバイオロジー概論 STATUS: Presented AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:2025 PUBLICATION TYPE: Conference PUBLICATION NAME: 61st Annual Symposium on Cancer Research Systems Biology of Cancer ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2008-10-31 TITLE: A Robustness-based Approach to Systems-oriented drug design STATUS: Presented AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:2026 PUBLICATION TYPE: Book PUBLICATION NAME: 理科年表 平成21年 ARTICLE TITLE: システムバイオロジー；生物をシステムとして理解する SUBMIT DATE: ACCEPT DATE: 2008-11-30 PUBLICATION DATE: 2008-11-30 TITLE: システムバイオロジー；生物をシステムとして理解する STATUS: Published AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:2027 PUBLICATION TYPE: journal PUBLICATION NAME: BIO INDUSTRY ARTICLE TITLE: システムバイオロジーの進展 SUBMIT DATE: 2008-09-04 ACCEPT DATE: 2008-12-12 PUBLICATION DATE: 2008-12-12 TITLE: システムバイオロジーの進展 STATUS: Published AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:2028 PUBLICATION TYPE: journal PUBLICATION NAME: 化学と生物 3月号 ARTICLE TITLE: システムバイオロジーの進展 SUBMIT DATE: 2008-12-16 ACCEPT DATE: 2009-03-01 PUBLICATION DATE: 2009-03-01 TITLE: システムバイオロジーの進展 STATUS: Published AUTHOR NAME: 北野宏明; 松岡由希子 AUTHOR AFFILIATION: システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:2029 PUBLICATION TYPE: journal PUBLICATION NAME: Pharma VISION NEWS 第13号 「薬学研究ビジョン」 ARTICLE TITLE: システムバイオロジー創薬：ロングテール・ドラッグとオープン・ファーマを目指して SUBMIT DATE: 2009-01-05 ACCEPT DATE: PUBLICATION DATE: TITLE: システムバイオロジー創薬：ロングテール・ドラッグとオープン・ファーマを目指して STATUS: Submitted AUTHOR NAME: 北野宏明 AUTHOR AFFILIATION: システム・バイオロジー研究機構 ------------------------------ PUBLICATION ------------------------------ PUBLICATION ID:2030 PUBLICATION TYPE: Conference PUBLICATION NAME: International Symposium of Translational Informatics 国際トランスレーショナルインフォマティクスシンポジウム (The 2nd International Symposium on Omics-based Medicine and Systems Pathobiolgy) ARTICLE TITLE: SUBMIT DATE: ACCEPT DATE: PUBLICATION DATE: 2009-03-24 TITLE: A Robustness-based Approach to Systems-oriented drug design STATUS: Submitted AUTHOR NAME: Kitano, H. AUTHOR AFFILIATION: The Systems Biology Institute |
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