AS-ALPS (Alternative Splicing-induced ALteration of Protein Structure)
Alternative splicing (AS) is a molecular mechanism that produces multiple proteins from a single gene, and is thought to increase the number of proteins extensively over the number of genes in a genome, which could be required to generate complexity of higher eukaryote including human. However, what roles most of AS variants play are not known.
This database, AS-ALPS (Alternative Splicing-induced ALteration of Protein Structure), is aimed at providing useful information to analyze effect of AS on protein interaction and network through alteration of protein structure.
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